항고혈압성 안지오텐신 전환효소 저해제를 생산하는 새로운 효모의 선별 및 저해물질 최적 생산조건

강민구; 김하근; 이성훈; 임성일; 이종수

한국균학회 한국균학회지 항고혈압성 안지오텐신 전환효소 저해제를 생산하는 새로운 효모의 선별 및 저해물질 최적 생산조건

Candidate SCOPUS

Research Articles : Screening New Antihypertensive Angiotensin I-Converting Enzyme Inhibitor -Producing Yeast and Optimization of Production Condition

강민구 ( Min Gu Kang ) , 김하근 ( Ha Kun Kim ) , 이성훈 ( Sung Hun Yi ) , 임성일 ( Sung Il Lim ) , 이종수 ( Jong Soo Lee )

한국균학회 2011.12

한국균학회지 vol. 39 iss. 3 194-197(4pages)

UCI I410-ECN-0102-2013-480-002223271

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Abstract

Forty eight strains of yeast were cultured in potato dextorse(PD) broth at 30˚C for 24 hr and centrifuged with 12,000 rpm for 20 min. After concentrated the cultures, antihypertensive angiotensin I-converting enzyme(ACE) inhibitory activities of its concentrates were investigated. Among them, the concentrates from Saccharomyces cerevisiae Y183-3 showed the highest ACE inhibitory activity of 71.8%. The ACE inhibitor from Saccharomyces cerevisiae Y183-3 was maximally produced when Saccharomyces cerevisiae Y183-3 cultured in PD broth at 30˚C for 36 hr.

Keywords

Antihypertensive angiotensin I-converting enzyme inhibitor

Potato dextrose broth

Saccharomyces cerevisiae Y183-3

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