Metastases involving central nervous system are relatively frequent in advanced cancer patients. The incidence of brain metastases has increased over time, probably as a result of advances in neuro-imaging procedures and improvements in the treatment of primary tumour and systemic disease, which has led to an increase of survival. Treatment for metastases involving central nervous systme includes corticosteroids, anticonvulsants to control seizures, surgery, radiotherapy, radiosurgery and chemotherapy. The appropriate aim of treatment is maintenance of quality of life. (Korean J Med 2011;81:307-314)