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KCI 등재 SCOPUS
천연물/유기화학 : 도화(桃花, Prunus persica Flos)의 미백 및 주름개선 효과
Whitening and Anti-wrinkle Effects of Prunus persica Flos
이진영 ( Jin Young Lee ) , 안봉전 ( Bong Jeun An )
UCI I410-ECN-0102-2012-520-001655294

The solvent extracts of Prunus persica Flos were investigated for the activities of whitening and anti-wrinkle effects to apply as a functional ingredient for cosmetic products. The tyrosinase inhibitory effect, which is related to skin-whitening, was 54.0, 58.3% in P. persica Flos (PPW, PPE) at 1,000ppm. In addition, the ethanol extract of P. persica Flos (PPE) showed a potent tyrosinase inhibitory activity in the test using melanoma cell lines resulting in 40.0% inhibition at 100ppm. Furthermore, the aqueous acetone extract from the flower of P. persica Flos was found to inhibit elastase, which was more effective than ascorbic acid at 1,000ppm. The inhibition of melanin synthesis by P. persica Flos extract (PPE) was about 56.5% at 100ppm concentration. When compared to other extraction methods, the ethanol extract showed more potent whitening activity. For anti-wrinkle effect, the elastase inhibition activity of P. persica Flos extract (PPA) was 57.0% and higher than that of ascorbic acid at 1,000ppm. The collagenase inhibition activity of P. persica Flos extract (PPA) was about 48.0% at 1,000ppm. Collagen synthesis in fibroblast cell by P. persica Flos extracts (PPA) was about 41.0% at 100ppm and its acetone extract was the best showing antiwrinkle activities. All these findings suggested that P. persica Flos has a great potential as a cosmeceutical ingredient with a whitening and anti-wrinkle effect.

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