Objective: The aim of this study is to investigate the effects of Taeyeumjoweetang (TJT) and Taeyeumjoweebaemahwangtang (TJBM) medication on body weight change and serum total cholesterol, HDL cholesterol, LDL cholesterol, triglyceride, free fatty acid, total lipid, phospholipid level, and CBC of obese rats. Methods: Obese rats induced by high-fat fed are medicated for 7 weeks. 32 rats are divided into four groups depending on the medication; normal group (general-fat fed and no-medication), control group (high-fat fed and no medication), TJT group (high-fat fed and TJT medication) and TJBM group (high-fat fed and TJBM medication). After 7 weeks, obesity related index and CBC are analysed. Results: There is a significant statistical difference between control group and TJBM group for the body weight change, the total cholesterol, HDL cholesterol, and triglyceride level: total cholesterol values of control and TJBM are 59.25±9.56㎎/㎗ and 39.13±9.08㎎/㎗, respectively; HDL cholesterol values of control and TJBM are 22.0±1.69㎎/㎗ and 13.75±2.19㎎/㎗, respectively; triglyceride values of control and TJBM are 12.75±3.37㎎/㎗ and TJBM: 8.13±1.64㎎/㎗, respectively. There is a significant statistical difference between control group, TJT, and TJBM group for free fatty acid and phospholipid level: free fatty acid values of control, TJT, and TJBM are 936.25±89.59㎛/ℓ, 738.75±109.47㎛/ℓ, and 720±150.71㎛/ℓ, respectively; phospholipid values of Control, TJT, and TJBM are 87.13±11.86㎎/㎗, 70.5±12.22㎎/㎗, and 60.5±11.1㎎/㎗, respectively. Conclusion: These results suggest that medication of TJT and TJBM is effective for the treatment of obesity. Especially, TJBM is more effective than TJT.