전신성 홍반성 루푸스 자체에 의한 간염은 드물게 발생하며, 자가면역성 간염과 감별을 요한다. 저자들은 자가면역성 간염과 유사하게 표현된 루푸스 간염에서 간 조직검사의 중요성을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Patients with systemic lupus erythematosus (SLE) have a 25% to 50% incidence of abnormal findings on liver function tests. The main causes of abnormal liver function in patients with SLE are viral hepatitis, drug-induced toxic hepatitis, and fatty liver. However, hepatic involvement due to the pathogenic process of SLE is rare. In such conditions, lupus-related hepatitis must be distinguished from autoimmune hepatitis, which is a type of primary liver disease characterized by similar clinical manifestations and autoimmune profiles. Relationships between hepatic involvement of SLE and autoimmune hepatitis remain to be elucidated. We report a case of lupus-related hepatitis mimicking autoimmune hepatitis. (Korean J Med 2011;80:360-364)