Suppressive Effects of Dihydroxyanthraquinone Derivatives against Inducible Nitric Oxide Synthase

Hoi Seon Lee

한국응용생명화학회 한국응용생명화학회지 Suppressive Effects of Dihydroxyanthraquinone Derivatives against Inducible Nitric Oxide Synthase

Accredited SCIE

( Hoi Seon Lee )

한국응용생명화학회 2010.12

한국응용생명화학회지 vol. 53 iss. 6 831-837(7pages)

UCI I410-ECN-0102-2012-520-001673069

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Abstract

Inhibitory effects of Cassia tora seed-derived materials against nitric oxide (NO) production were determined via evaluation of NO production. Inhibitory effects of 1,8-dihydroxyanthraquinone and 1,5-dihydroxyanthraquinone against NO production were 71.5 and 61.1% at 5 μg/mL, respectively. The suppressive effects of 1,8-dihydroxyanthraquinone completely blocked iNOS protein expression at 20 μM.

Keywords

Cassia tora

1

8-dihydroxyanthraquinone

functional food

inducible nitric oxide synthase

nitric oxide production

suppression

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