Short Communication : Antioxidative and Prolyl Endopeptidase Inhibitory Activities of the Phenolic Constituents Isolated from Phellinus Linteus

Young Sook Paik; Hye Ryeon Yoon

한국응용생명화학회 한국응용생명화학회지 Short Communication : Antioxidative and Prolyl Endopeptidase Inhibitory Activities of the Phenolic Constituents Isolated from Phellinus Linteus

Accredited SCIE

( Hye Ryeon Yoon ) , ( Young Sook Paik )

한국응용생명화학회 2010.10

한국응용생명화학회지 vol. 53 iss. 5 652-656(5pages)

UCI I410-ECN-0102-2012-520-001678675

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Abstract

Davallialactone (1) and inoscavin A (2) isolated from Phellinus linteus showed significant prolyl endopeptidase competitive inhibition with IC50 values of 20.0±0.1 and 12.2±0.1 ?M and Ki values of 15.6±0.3 and 8.3±0.1 ?M, respectively. They also exhibited strong antioxidant capacities against the ABTS radical system with EC50 values of 2.61±0.01, 13.3±0.05 ?M, respectively.

Keywords

prolyl endopeptidase inhibitor

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