Objective: This study is achieved to know the way that we can use metabolomics for the scientific research of Korean medicine. Results: We elucidate that metabolomics can be contributed to four ways for objectification of Korean medicine 1. Diagnosis of BeunJungLonChi(辯證論治). 2. Application toward Personalized medicine. 3. Quantification of Herbal medicine. 4. Evaluation of efficacy/safety for Korean medicine formulation Conclusion: Metabolomics opens up a new opportunity to reinvestigate Korean medicine from holistic perspective. Furthermore, Metabolomics is expected to provide effective method in research of acupuncture and meridian.