This study was produced to examine the effects of moxibustion that had been played role to traditional oriental medical treatment on disease. Before this article, we reported that Moxi tar decreased Nitric Oxide(NO) in activated RAW 264.7 cell by LPS and INF-gamma, which was decreasing Nitric Oxide Synthase(J. Kor. AM-Meridian & Pointology Soc. Vol.17, No.1, pp.33-46, 2000). And this article we used 12-O-Tetradecanoyphorbol-13-aceate(PMA) and LPS in C6-glioma cell line to produce Nitric Oxide(NO). And results was that Moxi-tar decreased NO in activated C6-glioma cell by LPS and PMA significantly. So we proposed that Moxi-tar had anti-inflammation and anti-cytotoxity in C6-glioma cell by decreasing Nitric Oxide.