칸디다와 거대세포바이러스 감염은 세포 매개성 면역이 저하된 환자에 있어서 기회감염의 원인으로 알려져 있다. 저자 등은 제2형 당뇨병 및 말기 신부전, 스테로이드, 면역억제제를 복용하고 있는 환자에서 상부 내시경검사 및 조직검사로 진단된 칸디다와 거대세포바이러스의 동시 감염에 의한 식도염 1예를 진단, 치료하게 되어 보고하는 바이다.

A 72-year-old man with end-stage renal disease who was taking oral steroids and immunosuppressive agents to control rheumatoid arthritis was admitted with complaints of anorexia and general weakness. Based on endoscopic findings and a histologic examination, the patient was diagnosed with infective esophagitis caused by Candida spp. and cytomegalovirus co-infection. Cytomegalovirus and Candida spp. are common causes of opportunistic infections; however, cytomegalovirus and Candida spp. co-infection is very rare. The patient was treated with ganciclovir and fluconazole. Endoscopic examination after 3 weeks showed improvement of the esophagitis. When endoscopy examination shows typical white spots that are indicative of Candida esophagitis, histologic and microbiologic studies should be encouraged for cytomegalovirus and Candida co-infection, especially in immunocompromised patients. (Korean J Med 79:82-86, 2010)