목적: 고안압증 환자에서 안압과 연령, 혈압 및 비만도의 상관관계를 알아보았다. 대상과 방법: 고안압증 환자 2,684명을 대상으로 혈압과 비만도를 측정하였다. 대상군을 20대에서 70까지 연령군으로 나누고, 안압과 성별, 혈압, 비만도와의 관계를 분석하였다. 결과: 평균연령은 48.0±11.0세로 평균안압은 22.04±2.2 mmHg였고, 평균안압, 혈압은 남성에서 여성 보다 유의하게 높았고(p=0.023, p=0.032), 비만도는 여성에서 유의하게 높았으나(p=0.002) 연령에 따른 차이는 없었다. 평균혈압 및 비만도로 보정한 연령과 안압과의 관계는 성별에 관계없이 유의하게 반비례하였다(p<0.001). 연령, 평균혈압으로 보정한 비만도와 안압과의 관계(p=0.001) 및 연령과 비만도로 보정한 혈압과 안압과의 관계는 성별에 관계없이 유의하게 비례하였다(p<0.001). 결론: 고안압증에서 안압은 혈압, 비만도와 연관성이 있었고, 성별에 상관없이 연령이 증가할수록 안압은 감소하였으나 평균혈압이 높을 때는 안압은 증가하므로 고혈압이 있는 고안압증의 경우 정기적인 안압의 경과 관찰이 필요하다고 생각된다. <대한안과학회지 2009:50(7):1082-1087>

Purpose: To evaluate the relationship between intraocular pressure (IOP) and age, blood pressure and obesity index inocular hypertensive patients. Methods: A total of 2684 ocular hypertensive patients underwent automated multi-phasic testing, including fundus photography, blood pressure and assessment of obesity. The subjects were divided into six age groups by decades ranging from 20~29 years to over 70 years of age. The relationships between factors were examined using multiple regression analysis. Results: The mean participant age was 48.0±11.0 years, and 1,777 (66.3%) participants were male and 907 (33.7%) were female. The mean intraocular pressure (IOP) was 22.04±2.2 mmHg and was significantly higher in males than in females (p=0.023). The IOP was associated with mean blood pressure, gender and obesity index. After adjustment for mean blood pressure and obesity index, the relationship between IOP and age showed a significantly negative tendency (p<0.001). The relationship between IOP and obesity index adjusted for age and mean blood pressure had a significantly positive tendency (p<0.001), regardless of gender. The relationship between IOP and mean blood pressure adjusted for age and obesity index showed a significantly positive tendency (p=0.00014). Conclusions: IOP was associated with the mean blood pressure and obesity index. Regardless of gender, IOP decreased with age but increased with hypertension. It is necessary to check IOP regularly, especially in ocular hypertensive patients with systemic hypertension. J Korean Ophthalmol Soc 2009;50(7):1082-1087