발열, 전신 근육통을 주소로 내원하여 시행한 혈청검사에서 급성 A형간염으로 진단된 환자에서 A형간염 이환기간 중 횡문근융해증이 발생하여 수액요법 및 보존적인 치료로 호전된 사례 1예를 경험하였기에 문헌고찰과 함께 보고한다.

A 29-year-old man was admitted to hospital with fever, myalgia, and sore throat. Initial laboratory findings were compatible with acute hepatitis; he was positive for the serologic marker for acute hepatitis A. On the 3rd day of admission, in spite of normalization of body temperature and a reduction in serum liver enzyme levels, serum levels of creatinine phosphokinase had increased up to 16,949 U/L. The patient recovered with supportive therapy and was discharged on the 12th day. We report a case of acute hepatitis A complicated by rhabdomyolysis during hospitalization. (Korean J Hepatol 2008;15:85-89)