This study was carried out to investigate the effect of clothing habit on physiological adaptation to the change of season. The survey of clothing weight in fall & winter for 2 years, the frequency of cold infection in winter and degree of fatigue was performed with 110 female high school students. The actual condition of clothing and the correlations between clothing weight and cold infection, and between the clothing weight and degree of fatigue were suveyed. The results are followed as; 1. The clothing insulation was nearly same to indoor standard clothing insulation in H kun wearing normal clothing, but was higher 2 clo in S kun clothed uniform. Especially in spite of similar enviromental condition the clothing weight, minimum & maximum and variation of clothing weight for 2 years were showed to be heavier in S kun than H kun. Also indoor thermal sensation felt by the subjects indicated "cold", and the difference between clothing insulation and standard clothing insulation showed increase gradually. 2. L group was indicated to be lower in cold infaction ratio than M & H group, and the correlation between clothing group and cold infection ratio was recognized to be significant (p<0.05). And H kun and L-H group showed to be lower in cold infection ratio than S kun, H-L group. 3. The coefficience between clothing weight and degree of fatigue was recognized to be significant (p<0.05).