We assumed that the sea organism in the Jeju Island might have stronger tolerance against ultraviolet ray than other regions, so we divided and cultured Jeju Island marine algae such as Eclonia cava, and then we researched the protection and therapeutic effect of apoptosis from the extracted materials, and also analyzed the anti-oxidant activity Eclonia cava had 30.00±2.90 ㎍ / ㎖ of IC50 value for DPPH radical scavenging activity, it`s anti-oxidant activity was lower than the control group BHA or Trolox, however it was higher than curcumin. Superoxide also when 40.82±2.48 ㎍/㎖ of extract material added, it had 50% of radical scavenging effect, and it`s IC50 value was lower than the control group trolox or quercertin, so its anti-oxidant effect was considered to be high. For nitric oxide radical scavenging activity, its IC50 value was 30.54±2.48 ㎍/㎖, and it is higher than the control group quercertin or curcumin, so its anti-oxidant effect was low, however, when 1000 ㎕ / ㎖ was added, Eclonia cava had 100% inhibition effect, so its anti-oxidant activity was high. For xanthine oxidase inhibitory activity, superoxide (IC50 12.08±0.53 ㎍/㎖) and uric acid (IC50 25.04±2.60 ㎍/㎖) had low generation interrupting activity, compared to the control group L-ascorbic acid and trolox, it had better anti-oxidant effect. Eclonia cava in Jeju Island had 0% in MTT assay, so they had no skin cell protection effect. These study results will suggest a new reason why Jeju Island sea organism treatment effect and antioxidant effect against apoptosis are proven, and can be used to prevent aging and disease.