Our synthesis began with octol, which were synthesized by condensation of resorcinol and hydrocinnamaldehyde. Tetrahydroxy cavitand 1 synthesis began with octol, which were synthesized by a four steps. Tetrakis (2-pyridylmethyl)amide cavitand 3 and tetrakis(3-pyridylmethyl)amide cavitand 4 were prepared from tetrakis [(methoxycarbonyl)me - thyloxyl cavitand 2 with 2-(aminomethyl)pyridine and 3-(aminomethyl)pyridine. The abilities of synthetic receptors, such as cavitand 3 and cavitand 4, to mediate the transport of cation through a liquid chloroform membrane were determined. The transport rate of metal ion depend on the nature of cation. For the various metal ions, the order of transport rate is Li^(+) ＞ Na^(+) ＞ K^(+) of tetrakis(2-pyridylmethyl)amide cavitand 3 and Ca`` ＞Mg``＞K^(+)＞ Na` of tetrakis(3-pyridylmethyl)amide cavitand 4.