Tensile and fracture behaviors of double-forged and aged Ti-6Al-4V alloys, with and without solution heat treatment and/or rapid cooling, were examined in the present study. Depending on the forging temperature and heat treatment condition, the microstructures of Ti-6Al-4V alloys varied greatly, including equiaxed α+transformed β. elongated α+equiaxed α, α` or acicular α in the prior β grain, and significantly affected the tensile and fracture properties at 25 and 316℃. Tensile and fracture failure modes of Ti-6Al-4V alloys with different microstructures were discussed based on the detailed fractographic examinations.