Synthesis and Configuration Determination of Styrylquinolines as Leukotriene D4 Antagonist Precursors

Dong Soo Koh; Bon Jeong Koo; Yeon Joong Yong; Yoong Ho Lim

한국응용생명화학회 한국응용생명화학회지 Synthesis and Configuration Determination of Styrylquinolines as Leukotriene D4 Antagonist Precursors

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Synthesis and Configuration Determination of Styrylquinolines as Leukotriene D4 Antagonist Precursors

( Dong Soo Koh , Bon Jeong Koo , Yeon Joong Yong , Yoong Ho Lim )

한국응용생명화학회 1998.06

한국응용생명화학회지 vol. 41 iss. 4 261-264(4pages)

UCI I410-ECN-0102-2008-520-001466614

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Abstract

Differently substituted styrylquinoline derivatives (6-9) were synthesized by condensation of quinaldine (1) and corresponding substituted benzaldehydes (2-5). Their relative configuration at C11-C12 and coupling patterns were determined by NMR techniques.

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