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SCIE SCOPUS
체중 , 성별 및 열량제한이 돼지의 Lipoprotein Lipase ( LPL ) 의 유전자발현과 LPL 의 활성도에 미치는 영향
Effects of Body Weight , Sex and Energy Restricition on Lipoprotein Lipase ( LPL ) Gene Expression and LPL Activity in the Growing Pigs
정정수 , 이재준 , 김진걸 ( C . S . Chung , J . J . Lee , J . G . Kim )
UCI I410-ECN-0102-2008-520-001472518
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The current study was undertaken to determine the effects of increasing body weight, sex, and energy restriction on the LPL mRNA abundance and LPL activity of adipose tissue in the finishing pigs. Serum lipoprotein pattern. triglyceride concentrations and their correlation with LPL activity were also investigated. Serum total cholesterol(C). HDL-C. LDL-C and HDL-C/T-C ratio were not significantly affected by body weight. sex or energy restriction. The triglyceride concentration increased with increasing body weight, being greater in gills than in boars(p$lt;0.05). The serum triglyceride concentration of full-fed pigs tended to be higher than that of energy-restricted pigs. Heavier pigs showed higher LPL activity than lighter pigs(p$lt;0.05), gills showing higher LPL activity than boars. and full-fed pigs showing higher LPL activity than energy-restricted pigs. Gills showed higher LPL mRNA abundance than boars, full-fed pigs showing higher LPL mRNA abundance than energy-restricted pigs. However. there was no significant difference between heavier and lighter pigs in the LPL mRNA abundance. The LPI_ activity was correlated with the triglyceride concentration, but not with the HDL-C, in individual experiments except the energy-restriction experiment. These results suggest that LPL is an important indicator for lipogenesity in pigs.

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