마비성패류독(Paralytic shellfish poison, PSP)에 의하여 독화된 패류의 유효이용에 대한 자료를 제공하고자 독화된 진주담치의 중장선 균질육, 0.1N HCl로 추출한 조독소 용액, 중장선으로부터 정제한 gonyautoxin(GTX) group과 saxitoxin(STX) group 등 4가지 형태의 PSP 독소에 대한 내열성을 조사하였다. 독화된 진주담치의 중장선육 균질액, 산추출 조독소액, GTX group, STX group 등 4 종류의 반응속도상수는 120℃에서 3.28×10^(-2), 1.20×10^(-2), 5.88×10^(-2), 2.58×10^(-2)이었으며 4 종류의 독소 중 0.1 N HCl 추출한 조독소용액의 D-value가 가장 높았다. 반응속도상수를 이용한 살균온도 산정에 있어서, 초 독력이 200 /100g인 독화된 진주담치육의 경우, 독력을 마비성패류독 규제치인 80 ㎍/100g으로 감소시키는데에는 90℃에서는 약 129분, 100℃에서는 약 82분, 110℃에서는 약 48분, 120℃에서는 약 28분이 걸렸다. 이러한 결과는 최초 독력이 200 ㎍/100g인 패류의 경우, 통조림 살균공정 후 잔존 독력이 규제치인 80㎍/100g이하로 감소시키는데에는 현재의 살균조건(115℃, 70분)으로는 충분하다는 것을 입증한다

The purpose of this study was to determine the kinetics of paralytic shellfishpoison (PSP) destruction at various temperature. The toxic digestive gland homogenate of bluemussel (Mytilus edulis), PSP crude toxin, gonyautoxin group and saxitoxin group were heated attemperature ranging from 90 to 120"C, and then the toxicities were measured in samples heatedfor various time intervals. The rate constant (k) of the toxic digestive gland homogenate, PSPcrude toxin, gonyautoxin group and saxitoxin group were 3.28 ~ 10.2, 1.20 ~ 10-*, 5 . 8 8 ~ 10.` and 2.58x 10.` at 120"C, respectively. The decimal reduction time (D-value) of the toxic digestive glandhomogenate, PSP crude toxin, gonyautoxin group and saxitoxin group were 70, 192, 39 and 89at 120"C, respectively. These results indicate that PSP crude toxin is most heat-stable of 4 typesof PSP toxins and PSP toxin are more heat-stable than food poisoning bacteria and spores. Theretorting condition to reduce PSP toxicity below quarantine limit (80 pgI100 g in Korea and Am-erica, 4 MU/g in Japan) could be calculated by rate constant. For example, the digestive glandhomogenate having a initial toxicity of 200 pgI100 g could have toxicity below quarantine limitwhen heated at 90 C for 129 min., 100 C for 82 min., 110 C for 48 min. and 120 C for 28 min.These results suggest that commercial retorting condition (115 C for 70 min) in Korea is enough toreduce toxicity below quarantine limit from initial toxicity of 200 pg/lOO g. From these results, thequarantine limit of PSP-infested shellfish for canning can be level up to raw score of 200 pg/100g.