Two experiments were conducted to determine the nutritional value of spray-dried porcine plasma (SDPP) and wheat gluten (WG) in diets for early-weaned pigs. In Experiment 1, 144 weanling pigs were used in a growth assay for 35 days. Experimental diets fed from day 0 to 14 postweaning were 1) a dried skim milk (DSM)-dried whey-soybean meal based as control and 2) and 3) SDPP and WG used to replace DSM on a protein basis. All pigs were fed the same corn-soybean meal-dried whey-based diet from day 14 to 35. For day 0 to 14, pigs fed SDPP had greater feed intake than pigs fed WG (P$lt;0.05). However, for day 14 to 21 (i. e., during the transition period to the Phase II diet), pigs fed diets with WG had the greatest rate of gain and feed intake compared with pigs fed DSM or SDPP during Phase I (P$lt;0.05). Overall, pigs fed diets with WG or SDPP had greater rates and efficiencies of gain than pigs fed DSM (P$lt;0.05). In Experiment 2, 108 weanling pigs were used in a growth assay for 35 days to determin the optimal blend WG and SDPP for use after weaning. Treatments were 1) 100% SDPP, 2) 50% SDPP and 50% WG, and 3) 100% WG. Similar to Experiment 1, all pigs were switched to common corn-soybean meal-dried whey-based diet for day 14 to 35. For day 0 to 14, there were no differences in growth performance. However, there was a quadratic response in gain/feed, with pigs fed the 50:50 blend having the lowest gain/ feed for day 14 to 35 and day 0 to 35 (P$lt;0.05). There was no difference in DM digestibility at day 13 postweaning. However, there was linear response in N digestibility when WG was increased (P$lt;0.10). In conclusion, SDPP improves growth rate for the initial postweaning phase. However, feeding WG during Phase I results in improved growth performance during the transition to the Phase II diet.