A case of spindle cell tumor was presented in a 16-month-old, female syrian hamster. In the left chest are, a 3㎝ firm elevated recurrent mass was found, surgically removed, and submitted to the Department of Veterinary Parthology, Seoul National University for diagnosis. The mass was soft to firm and tan on sectioning, and contained hemorrhagic area. Histologically, the tumor was composed of sheets of interlacing bundle of spindle-shaped cells with moderate amount of cytoplasm and oval to fusiform nuclei. They were pleomorphic and contained 1 to 3 prominent nucleoli. Based on the gross and histological findings, the tumor was diagnosed as a subcutaneous spindle cell tumor. However, the exact origin of neoplastic cell remained undetermined.