We observed and anatysed relating probiems conamed to 21 patients of the acute carbamate intoxications, the emergency room of cheonju Presbytaian Medical center, from Oct 1993 to July 1996. The results were as follows 1) Male was more prevalent than female with a ratio of 2: 1 in sex distribution and the highest inddence of age group was in third decade and sixth decade of age in male sex 2) The most common drug of intoxication was deltanet in 7 cases, the remainders were bassa in 3 cases, b.p in 3 cases, huradan, qratel and methomyl in 2 cases, each, in order of hequency 3)Among the exposed carbamate in 13 patients with respiratory fallure, detanet was the most common in 6 cases, b p in 3 cases, methomyl in 2 cases, bassa and huradan each in 1 case 4) The serum ChE activity of patients were significantly reduced compare to normal 8 patients were between 20~50% of normal, 8 patients were above 50% of normal, 4 patients were between 10~20% of normal, only 1 patient was below 10% of normal 5) In 13 patients with respiratory failure, serum ChE activities were below 50% of normal. 6) In all patients with respiratory failure except 1 case time to recovery of the respiratory failure was below 48hrs. 7) Mean dose of atropine administered within first full atropinization and first 24 hours was significantly higher in patients with than patients without respiratcey failure in staitistics(29.3 ±23.3mg, 54.5 ±49.5mg VS 7.6 ±3 6mg, 13.6 ± 6.9mg). 8) 3 patients among a total of 21 patients expired So that motality rate was 14.3%. Among the expited cases, 1 patients discontinued treatrnent due to economic problems and only 2 patients died in hospital during the treatment