Ocular lesions induced in 40 specific-pathogen-free Marek`s disease (MD) resistant chicks by inoculation at 1 day of age with very virulent strain of Marek`s disease virus (MDV) were pathologically examined. Grossly, 24/40 (60%) chicks had white gel-like materials in the vitreous body, whereas thickening and discoloration of iris (gray eye) were not observed. Microscopically, characteristic ocular MD lesions were observed in choroid (27/40), ciliary (30/40) and iris (23/40) in which small focal inflammatory to diffuse neoplastic lymphoid cells were infiltrated. Five out of 40 MDV-inoculated birds revealed necrotizing lymphomas in choroid. These lesions consisted of necrotic and degenerating lymphoblasts accompanied by intranuclear inclusion body. There was retinal atrophy and necrosis with inclusion body detected in necrotic ganglion, inner or outer nuclear and infiltrated lymphoblast cells. Conjunctiva showed lymphoid cell infiltration in 29/40 chicks inoculated with MDV. Vitreous body exhibited mild to severe exudation of eosinophilic proteinaceous material in 24/40 chicks. Theses lesions were associated with lymphoid cell infiltration, edema and fibrosis of choroid. Pecten (7/40) and optic nerve (13/40) were infiltrated usually mildly with lymphoid cells. From these results, very virulent strain, Md/5 of MDV caused high incidence of ocular lesions in MD resistant chicks. In addition, Md/5 induced exudation of proteinaceous material into the vitreous body and fibrosis of choroid. Necrotizing ocular lymphoma lesions in choroid is the first report in the MD literature.