Gallstone pancreatitis should be treated with a proper Surgical approach in the appropriate timing. We clinically reviewed 58 patients with gallstone pancreatitis which were treated by laparotomy during a 5-year period from Jan. 1989 to Dec. 1993 and reached conclusions as follows. 1) The mean age was 56.3 years and the male to female ratio was 1:1.15. 2) The incidence of gallstone pancreatitis was 11.7% of cholelithiasis and 35.6% of pancreatitis. 3) The most common symptom was upper abdominal pain 100%, and other symptoms and signs were jaundice 50%, nausea & vomiting 36.2%, and fever and chills 41.3%. 4) In location of gallstones, calculi only in GB were noted in 46.0%, in GB & CBD 31%, and in CBD including intrahepatic ducts 22.4%. 5) A first diagnostic tool used for diagnosis of gallstones was ultrasonography in 55.2% and CT in 36.2%. 6) In biochemical values on admission, SGOT was increased in 52 patients, SGPT in 54 patients, total bilirubin in 51 patients and serum amylase in 58 patients. 7) Cholecystectomy with T-tube choledochostomy was the most common surgical procedure in 28 patients(48.3%), and cholecystectomy in 24 patients(41.4%) and others in 6 patients(10.3%). 8) The only 4 patients with gallstone pancreatitis were severe form by modified Glasgow criteria. 9) On bile culture, the growth of E. coli was most commonly noted in 46.5%, but no growth of bacteria noted in 18.9%. 10) Postoperative complications were developed in 9 patients(15.5%), which were wound infection, retained stone, abscess and pulmonary complication. 11) In thc patients operated on within 48 hous of admission, the average duration from operation to discharge was 15.1 days; in the patients operated on after 48 hous of admission, the average duration from operation to discharge was 18.3 days.