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양측성 부신피질 선종에 의한 쿠싱증후군 1 예
A Case of Cushing`s Syndrome due to Bilateral Adrenocortical Adenomas
원욱희(Uk Hee Won),성순희(Soon Hee Sung),박정수(Jung Soo Park),허갑범(Kap Bum Huh),이현철(Hyun Chul Lee),정윤석(Yoon Sok Chung),라선영(Sun Young Rha),김진안(Jin Ahn Kim)
UCI I410-ECN-0102-2009-510-004684196

ACTH-independent Cushing`s syndrome is caused by autonomous production of cortisol, usually by an adrenal adenoma, carcinoma, or primary adrenocortical micronodular dysplasia. Cushing`s syndrome due to adrenocortical adenoma usually has a unilateral lesion and contralateral site becomes atrophic. We report a rare case of Cushing`s syndrome caused by ACTH-independent bilateral adrenocortical adenomas. A 48-year-old woman presented with Cushingoid features, diabetes mellitus and hypertension. Urinary free cortisol and 17-hydroxycorticosteroid excretion were 365.4 ug/ day and 16.2 mg/day, respectively. Both were not sup- pressed after administration of high-dose dexamethsone. Plasma ACTH was 3.5 pg/ml. Abdominal C-T revealed well defined bilateral adrenal tumors 4.0 cm in diameter on the ventral side of the right renal upper pole and 2.0 cm in diameter on the ventral side of left renal upper pole. Bilateral partial adrenalectomy was performed. The both adrenal glands showed all the pathologic features of adenoma.

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