Amiodarone, a class III antiarrhythmic drug containing iodine, is widely used for treatment of liftthreatening refractory cardiac arrthmias in Korea, The drug has a variety of complex effects on thyroid hormone physiology and occasionally causes clinically overt hyperthyroidism and hypothyroidism. Recently we experienced a case of thyrotoxicosis induced by lowdose amiodarone therapy for control of paroxysmal supraventricular tachycardia due to Wolff-Parkinson-White syndrome that went into euthyroid remission on withdrawal of the drug. We presents a case of amiodarone-induced thyrotoxicosis, firstly reported in Korea, with literature review.