A 17 year old girl underwent a surgery of spine fusion for a tuberculous cervical spine (C(4~5) ) under halothane-0₂ anesthesia. On the 1st postoperative day, sudden high fever(39.7C) with chillness and leukocytosis with eosinophilia were noted. On the following day, generalized jaundice, right hypochondralgia and slight hepatomegaly with marked impairment of liver function tests were noted. HB antigens were negative and there was no transfusion history of blood or blood products. About 2 months after operation, she was discharged with symptomatic improvement and almost normal laboratory data