Solitary splenic metastasis of colon cancer is uncommon and usually occurs with wide spread dissemination of the tumor. Only 8 cases of isolated splenic metastasis from colon cancer are reported in the English literature. A 26-year-old male who had received a right hemicolectomy for right colon cancer on May 1996, was hospitalized for increased carcinoembryonic antigen (CEA) level that was identified on regular follow-up. The abdomimal computed tomography (CT) revealed a 5×4×3.5 cm sized low attenuated lesion in posterior portion of spleen. On sono-guided aspiration, metastastic adenocarcinoma was confirmed. Under the diagnosis of solitary splenic metastasis, a splenectomy was performed on July 1998. We report the case with a review of literature. (Kor J Gastroenterol 2000;36:542 - 546)