Wandering spleen is a rare condition characterized by laxity or absence of the supporting splenic ligaments, in which a long pedicle allows the spleen to migrate from its normal position in the left upper quadrant. The patients are usually asymptomatic. When torsion of the pedicle occurs, a variety of clinical manifestations from mild intermittent abdominal pain to acute abdominal crisis may occur. We experienced a case of wandering spleen mimicking tumor in the left lobe of the liver in a 65-year-old female, and the spleen scan was useful for the diagnosis. (Kor J Gastroenterol 2000;36:128 - 131)