We retrospectively studied 34 patients with peritoneal seeding among 331 patients of stomach cancer who were received operation at the Department of Surgery, College of Medicine, Soon Chun Hyang University for 5 years from January 1986 to December 1990. The ages ranged from 31 years old to 70 years old (mean age 54) and most frequent age group was seven dedcades in 41.2%. The ratio of male to female was 1.8: 1. The duration of symptoms was less than 3 months in 29.4%, less than 6 months in 60.3%, and more than 1 year in 22.4%. The chief complaints were epigastric pain and discomport in 97.1%, weight loss in 79.4%, indigestion in 79.4% and nausea in 53%. The abnormal physical findings were epigastric tenderness in 55%, anemia in 32% and abdominal mass in 14.7%. The location of tumors was antrum and pylorus in 50%, body in 14.7%, cardia and fundus in 5.9% and entire stomach in '29.4%. The size of tumors was above 7cm diameter. in 58.8% and 3~6 cm diameter in 41.2%. In Borrmann's classification, the most common type was Borrmann's type III in 64.5%. Serum CEA was measured on 31 cases of 34 patients and the patients with high abnormal serum CEA range were 55.9%. Delayed cutaneous hypersensitivity responsiveness of Multitest CMI was quantified by a score (the sum of the diameters of induration). The average scores were 9.24 mm in male, 7.27mm in female and 8.56mm in total. There was no significant difference between male and female (p>0.05). But very significant difference between stomach cancer group and control group was present (p<0.001). In the pathologic findings, all of the cases were adenocarcinomas and the rnost frequent type was poorly differentiated adenocarcinonma in 43.3% Operative procedures undertaken were resectional surgery in 38.2%, bypass surgery in 32.4% and exporation in 23.5%. The overall median survivaI month was 7 months, 1/2 Y.S.R. was 55.6%, 1 Y.S.R. was 22.2% and 2 Y.S.R was 11.9%. In conrlusion, accurate diagnosis of stomach cancer with peritoneal seeding is difficult and the prognosis of these patients is very poor. Therefore, we suggest that aggressive treatments such as intraperitoneal chemotherapy or intraperitoneal hyperthermic perfusion after cytoreductive surgery, should be performed to improve survival of stomach cancer with peritoneal seeding