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18.97.14.87
18.97.14.87
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Candidate
위 상피 이형성의 치료방침
Therapeutic Strategy for Gastric Epithelial Dysplasia
민진식(Jin Sik Min),노성훈(Sung Hoon Noh),김호근(Ho Guen Kim),류창학(Chang Hak Yoo),이용찬(Yong Chan Lee)
UCI I410-ECN-0102-2009-510-004926533

Background/Aims: The purposes of this retrospective study are to analyse the clinicopathological characteristics and treatment results of the gastric epithelial dysplasia (GED) and to establish a rational therapeutic strategy for GED. Methods: From 1993 to 1995, the 67 patients who were initially diagnosed as GED by examination of endoscopic biopsies were reviewed after categorizing according to Morson's classification as mild (G1, n=10), moderate (G2, n=31), and severe (G3, n=26) GED. Results: Dysplastic changes were not detectable at follow-up in 60% of G1 cases and 13.8% of G2 cases. Endoscopic mucosal resection was performed in a total of 30 cases: 2 in G1, 19 in G2, and 9 in G3 and the results were fine except 5 cases of recurrence or positive resection margin. Gastrectomy was performed in 30 cases: 2 in G1, 19 in G2, and 9 in G3. Gastric cancer was detected in 21 cases. The 20 cases of them were at early stage (early gastric cancer) and 1 case was at advanced stage. In addition, lymph node metastasis was found only in 1 case of submucosal cancer. Conclusions: The therapeutic strategy for GED, especially in high grade, might be endoscopic mucosal resection or gastrectomy considering the patients' age, general condition and the size and the location of the dysplastic lesion. (Kor J Gastroeaterol 1998;32:176 - 183)

[자료제공 : 네이버학술정보]
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