Autoirnmune hepatitis is a chronic necroinflammatory liver disorder of unknown cause associated with circulating autoantibodies and a high serum globulin level. This disease occurs predominantly in young wornen, but rarely in postmenopausal woman. A variety of immunosuppressive agents have been used for the management. However, corticosteroid treatment in postmenopausal woman have a higher cummulative frequency of long-term complications and a lower net henefit-risk ratio than in premenopausal woman. A 69-year-old female was diagnosed to have autoimmune hepatitis in our hospital. We report this case with literature review. (Korean J Gastroentrol 1998;31:258 - 262)