Background/Aims: The aim of this study was to investigate the correlation of esophageal symp- toms with esophageal manometric assessment in progressive systemic sclerosis(PSS). Methods: We performed esophageal manometry and Bernstein test in 13 patients with PSS who were admitted to Seoul National University Hospital from Aug. 1990 to July 1992 and in 19 normal subjects. Results: Esophageal symptoms such as dysphagia, substernal pain and food regurgitation were recognized 8 out of 13 patients(62%). There was abnormal manometric finding in 11 out of 13 patients(85%). All patients with esophageal symptoms(100%) showed abnormal manometric findings. There was decreased low esophageal sphincter pressure in 7 out of 13 patients(54%). Those patients with esophageal symptoms showed more remarkably decreased low esophageal sphincter pressure(7.5 +4.8 vs 14.8 t 6.2 mmHg; p C0.05). Those patients with esophageal symp- toms showed more remarkably decreased amplitude of lower esophageal body contractions(3.0 1.6 vs 20.0 7.1 mmHg; p(0.001). 9 out of 13 patients(69%) showed loss of norrnally propagating peristaltic waves. There was significantly decreased amplitude of upper esophageal body contractions in PSS patients with esophageal sytnptoms. Those patients with esophageal symptorns showed more decreased amplitude of upper esophagea1 body contractions than those patients without symptom(7.3+3.6 vs 30.4+11.6 mmHg; p<0.005). Bernstein test was performed in 8 out of 13 patients. There were two positive cases who had esophageal symptoms. Conclusions: The results of this study showed that there were decreased amplitude of upper esophageal body contractions as well as decreased amplitude of lower esophageal body contractions and lower esophageal sphincter pressure in PSS. Those PSS patients with esophageal symptoms showed more decreased amplitude of upper and lower esophageal body contractions and more decreased lower esophageal sphincter pressure than those PSS patients without esophageal symptoms. (Korean J Gastroenterol 1996; 28:477 - 483)