In order to compare serum ferritin levels in each groups, the serum ferritin and serum transaminase were measured in 38 normal adults, and 50 patients with HBeAg carriers, 253 patients of various liver diseases (31 patients with acute hepatitis, 80 patients with chronic hepatitis, 119 patients with liver cirrhosis, 23 patients with hepatoma) who were admitted to St. Columban hospital from January 1989 to December 1989. Then we evaluated the relationship of serum ferritin levels in each groups. The following results were obtained. 1) The serum ferritin levels in 38 normal adults were 225 +- 71.06 ng/ml, and 215.50 +- 63.26 ng/ml in HBeAg carriers, but there was no correlatin in two groups. 2) Ferritin levels in each disease groups were higher than normal adults except acute hepatitis and that of liver cirrhosis was significantly elevated (p<0.01). 3) There was no significant correlation in the levels of serum ferritin with the serum ALT activities. 4) Serum ALT was significantly elevated in HBsAg positive patients than HBsAg negative patients in each liver diseases. In conclusion, there was no significant elevation of serum ferritin levels in HBeAg carriers compared with non-carriers.