Typhoid fever often causes changes indicative hepatic involvement. But icteric typhoid hepatitis, mimicking the clinical feature of acute hepatitis, is uncommon. A 48 year old man was admitted to the hospital because of jaundice, fever and weakness. Physical examination revealed mild hepatomegaly. Bilirubin was 4.0 mg/dl, GOT and GPT were 116/80 unit/ L on admission. Culture of stool grew of salmone! la typhi. Liver biosy revealed disarrayed hepatic cell cords by hepatocellular swelling and distended sinusoid, the focal necrosis of hepatocytes with Kupffer cell proliferation and mononuclear cell infiltration. These histological findings were those of so callednon specific reactive hepatitis. With the administration of chloramphenieol, ampicillin and bactrim, he became afebrile with subsidence of jaundice.