The fact that gastric mucosal lesions are frequently seen in portal hypertension is already well known. In recent years, many workers reported that endoscopic features of gastric mucosa with portal hypertension showed minimal inflammation and marked venous ectasia and dilatation.
However, the pathogenesis and pathophysiology and the diagnostic value of portal hypertension of these changes have been argued by many authors. Our purpose of the study is concerned about the incidence and the significance of congestive gastropathy on various chronic liver disease.
For this aims, First, retrospectively the results of endoscopic features and liver biopsies of the 477 patients with abnormal liver function test were analyzed, investigated the incidence of these changes, and Second, prospectively selected 10 patients with normal liver function test and congestive gastropathy on the proximal part of the stomach, and unresponsive to anti-erosive medication, were under taken liver biopsies. The result was as follows; 1) The incidence of congestive gastropathy was similar in liver cirrhosts and in other types of chronic liver disease (p<0.05). LC 20.3% (38/187), CAH 16.8% (21/125), CPH 15.5%, (9/58), and others 14.3% (12/84). 2) In second study, 7 of the 10 patients undertaken liver biopsy probed to be the chronic liver diseases. 3) The liver function test of the one of the two who had no pathology on liver biopsy to be abnermal during follow-up 4 month in second study. These suggested that congestive gastropathy was found on various chronic liver disease and the possible stigmata even if without any other sign of the chronic liver disease.