Tuberculosis of the pancreas is a rare disorder, little reported in the literature. It may not develop primarily within the pancreas, and may occur secondary to a focus elsewhere in the body. A 50-year-old woman presented with weight loss, epigastric pain and palpable abdominal mass. A diagnosi of inoperab]e carcinoma of the panceas was made after radiologic evaluation. But tubercu- losis of the pancreas was confirmed by sono guided fine needle aspiration biopsy. Completely recovery resulted following the admmistration of antituberculous chemotherapy.