Dieulafoys lesion, also known as exulceratio simplex and submucosal arterial malformation is a rare cause of massive gastrointestinal hemorrhage. The entity was first described in 1884 by Gallard and later characterized by the French surgeon George Dieulafoy in 1896. The lesion appears to be a large tortuous submucosal artery which usually develops in the stomach and ruptures for reasons not well understood. Surgical intervention has been the therapy of choice in most reported cases. We report a case in which endoscopic ethanol injection was used successfully in the management of this lesion.