This is a report of two cases of adenocarcinoma in ileum of the small intestine. Ileal adenocar- cinoma has been noted at its rarity, etiology, distribution, and poor prognosis. Recently we experi- enced two interesting cases. One dveloped in 25 year-old rnan, and the other in 42 year old man, vho had treated by segmental resection and chemotherapy, was followed by development of gastric carcinoma after 8 year-survival.