Clinical observations were made at the Masan Korea General Hospital on 119 patients with primary carcinoma of the liver from March 1981 to December 1984 The following results were obtained: 1) The average age was 54. 5 years with the age ranged from 29 years old to 79 years old and the peak age incidence was in the 5th decade, amounting to 40.3% of the total. The ratio between male and female was 6.9:1 2) The chief complaints were pain in right upper quadrant of abdomen in 64.9% anorexia or indigestion in 51.3% epigastric discomfort in 47.9% fatigability in 43.7% and weight loss in 37.8%, in order of frequency. Physical examination showed hepatomegaly in 85.7% ascites in 37.8% edema in 31.9% and fever in 21.8% in order of frequency. 3) Liver function tests were revealed globulin elevation in 86.6% SGOT elevation in 79.8% hypoalbuminemia in 73.9% alkaline phosphatase elevation in 71.4% SGPT elevation in 51.3% and total bilirubin elevation in 40.3% in order of frequency. 4) HBsAg was positive in 54(45.4%) of the 119 cases and AFP was positive in 66(55.6%) of the 119 cases. It was observed that AFP is apt to be positive in the patient positive for HBsAg. 5) The presence of cold area could be demonstrated by liver scan in 92(77.3%) of 119 cases: 68.5% In the right lobe, 16.3% in the left lobe, 11.9% in both lobe and 3.3% in porta hepatis. 6) Pathological classification of 119 cases were 105 cases(88.2%,) of liver cell carcinoma and 14 cases(11.8%) of cholangiocellular carcinoma. 31(81.6%) of 38 cases were died within 6 month after biopsy.