Aplastic anemia is rare, severe complication of viral hepatitis. Over 200 cases have been reported in the literature, but only recently the virological studies have been carefully implicated. There have been reports of fatal aplastic anemia associated with type-A virus, type-B virus and non-A, non-B hepatitis. We report a 35-year-old man, who found to have severe aplastic anemia associated with fulminant hepatitis: Virological studies suggested that it was probably non-A, non-B hepatitis.