Histopathologic findings of gastroscopic biopsy under direct vision were made in 178 patients who complained vague gastrointestimal symptoms withont any focal lesions such as peptic ulcer, benign or malgnant growth etc in gastrointestinal tracts between February, 1979 and May,:1980. Fasting serum gastrin and secretin levels were also determined in those patients by radioimmunoassay. The resuls were as follows; 1) Overall incidence of histopathologically proven chronic gastritis was 79. 2% in Korean adults. Of all chronic gastritis(141 cases), the incidence of superficral, superficial atrophic, atrophic gastritis and gastric atrophy were 27. 7%, 86. 2%, R4% and2. 1% respectively. 2) Superficial inflammatory lesions in superfical atrophic gastritis were distributed more diffusely than those in superficial gastritis. Atrophic lesins were distributed diffusely in 24. 2 % of cases with atrophic gastritis, but only locally in all cases of supeificial atrophic gas- tritis. These fidings strongly suggest that the superficial gastritis may result in atrophic gastritis. 3) Fasting serum gastrin and secretin levels in various chronic gastritis revealed no sign- ificant difference comparing with normal control group.