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안 합병증이 동반된 아토피 피부염의 임상적 특징
Characteristics of Atopic Dermatitis Related to Ocular Complications안 합병증이 동반된 아토피 피부염의 임상적 특징
황선욱(Seon Wook Hwang),박성욱(Sung Wook Park),왕한영(Han Young Wang),윤일한(Il Han Yoon)
UCI I410-ECN-0102-2009-510-004770891

Background: Long-standing atopic dermatitis patients frequently predispose to ocular complications. The ectoderrnal origin of the epidermis and of many eye structures explain the fre~quent associations observed in atopic dermatitis. Objective: This study may help in evolving early diagnosis a~nd in formul~ating standard therapeutic strategies to prevent and treat ocular complications by studying the types, frequency and dermatological characteristics of each ocular complication in atopic dermatitis. Methods: We evaluated the ocular complications of 4I typical atopic dermatitis patients(26 males, 15 females) who had skin lesion around eyelids or complained of ocular symptoms. Results: Mean age of the patients was 17.7 years. The onset of atopic dermatitis was during infancy in 21 patients, during chiildhood in 15 patients, and during adult in 5 patients and their mean duration of disease was 13.8 years. Mild ocular involvements including blepharitis in 29 patients(58 eyes, 70.7%), keratoconjunctivitis in 29 patients(58 eyes, 70.7%) were seen. More serious com- plications which may lead to decreased visual function including cataracts in 5 patients(10 eyes, 12.1%), retinal detachments in 3 patients(5 eyes, 6.0%) were seen. All the patients who had these two s~erious complications had facial dermatitis. And other ocular invo~lvements including keratoconus in 2 patients(2 eyes, 2.4%), ocular herpes simplex in 1 patient(2 eyes, 2.4%), uveitis in 2 patients(2 eyes, 2.4%) were seen. Conclusion . It is important to perfonn an ophthalmologic examination in the earl~y period of disease in long-standing atopic dermatitis patients especially those who have facial dermatitis for the early diagnosis and treatment of serious sight-threatening complications.

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