Staphylococcal scalded skin syndrome(SSSS) is the term used for a collection of blistering skin disease induced by the exfoliative toxin of Staphylococcus aureus. It primarily affects neonates and young children, but cases have been reported rarely in adults. We report typical cases of generalized SSSS in two male children. They had generalized tender erythroderma and flaccid bulla with leaving a moist erythematous base resembling a scald and focal peeling of the skin, particularly on the face, neck, axilla, trunk and buttock. Methicilline sensitive staphylococcus aureus was cultured from throat in one patient and from local wound of nares in the other patient. Nikolsky's sign was present. Histopathologic finding revealed an epidermal splitting at the granular layer. (Korean J Dermatol 2000;38(11)：1531~1535)