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이형성 모반의 임상 및 병리조직학적 고찰 - 15 예에 대한 고찰 -
Clinical and Pathologic Findings of Dysplastic Nevus - Review of 15 Cases -
신상부(Sang Boo Shin),이동원(Dong Won Lee),이준영(Jun Young Lee),조백기(Baek Gee Jo)
UCI I410-ECN-0102-2009-510-004771494

Background: The dysplastic nevus is a rare form of melanocytic nevus, but the clinical criteria and histopathologic finding are still debated. There are no studies of dysplastic nevus in korea except a few case reports. Objective : This study was aimed to evaluate the clinical and histopathological characteristics of dysplastic nevus developed in korean. Methods: We reviewed the clinical and histopathologic finding of 15 patients diagnosed as dysplastic nevus on the biopsy. Results : The result were as follows; 1. The incidence of dysplastic nevus in our study was 9.9 cases/100,000 population 2. The subjects consisted of 9 males and 6 females. 3. The common onset of age was 11-20. 4. The common site of dysplastic nevus was the trunk. 5. The common pattern of lesional change was asymmetry and color variegation. 6. The common clinical findings of the dysplastic nevus was multiple, 5-12mm size, multipapular surface, ill-demarcated margin and brown/black color. 7. The pathologic findings including shoulder phenomenon, melanocytic nest, patchy lymphohistiocytic infiltration, melanophage, scattered atypical epitheloid cell, random atypia, anisokaryosis and no mitosis was shown in all the patients, but eosinophilic hyperplasia was shown in 13 patients. 8. The mild atypia in the Duke grading system was the most common. There was significant positive correlation between architectural and cytologic scores(Pearson correlation test, P<0.05, r=0.97). Conclusion : Although the incidence of the dysplastic nevus in our study was much lower than that of the west, the clinicopathologic findings were not different.

[자료제공 : 네이버학술정보]
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