Favre-Racouchot syndrome, also known as nodular elastosis with cysts and comedones, typically presents with large black open comedones, furrows, and nodules in the periorbital region and over the malar eminence. The pathogenesis of Favre-Racouchot syndrome is still uncertain. However it has been postulated that damage from ultraviolet radiation, combined with some unknown host predisposition, leads to the degeneration of the supporting dermal connective tissue. We report a case of Favre-Racouchot syndrome that developed on the applied area of topical corticosteroid for a preceding post-herpetic neuralgia lesion. This case is unique to suggest that the catabolic effect of corticosteroid is superimposed on the UV-induced degeneration of dermal connective tissue as a pathogenic mechanism of Favre-Racouchot syndrome. (Korean J Dermatol 2000;38(3):433~435)