A 9-year-old male child presented with a 1×1 cm sized cystic nodule and adjacent skin-colored papules on his right shoulder. The lesions were clinically diagnosed as an epidermal cyst and molluscum contagiosum. Histological examination of the cystic nodule showed an epidermal cyst containing molluscum bodies in its wall. We herein report an unusual case of molluscum contagiosum invading a pre-existing epidermal cyst. (Korean J Dermatol 2000;38(2):272~274)