Blastomycosis-like pyoderma is a rare reaction pattern to a superficial bacterial infection in persons with a variety of underlying coniditions, including inflammatory and neoplastic pathologic conditions, and in associaton with a primary immunodeficiency state. We describe a clinically recurrent blastomycosis-like pyoderma on the right ankle area in an otherwise healthy man. (Korean J Dermatol 1999;37(1): 116-118)