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피부사상균에 의한 육아종의 임상 및 조직학적 소견
Clinical and Histopathologic Findings of Dermatophytic Granulomas피부사상균에 의한 육아종의 임상 및 조직학적 소견
김광(Kwang Kim), 채영수(Young Soo Chae), 서기석(Kee Suck Suh), 김상태(Sang Tae Kim)
UCI I410-ECN-0102-2009-510-005417797

We reviewed the cliniccipat.hologic findings of 11 cases of dermatophytic granulomas. Patients consisted of 8 male and 3 females with a mean age of 45 years (range 5-80 years). The symptom was neither painful nor pruritic except one case. Skin lesions mimicked tuberculosis (2 cases), sporotriehosis (2 cases), calcinosis cutis (1 case) or eczema (1 case). The commonest sites involved were upper extremities, followed by legs, cace and scalp. The duration between the onset of the diseases and final diagnosis ranged 1 month to 3 years. Possible predisposing factors causing dermatophytic granulomas appeared to be due to application of steroid ointment (6 cases), diabetes mellitus (2 cases) and trauma (1 case). Histopathologic featured revealed suppurative folliculitis with fo eign body granuloma in most cases and lobular ponniculitis in 2 cases. With PAS and methenamine silver stains, hyphae and spores could be identified on the horny layers, within hair follicles and/or on the dermis in biopsy specimen.', of all cases. Culture of the causativi; organisms using dermal fragment on abouraud media demon-strated T. rubrum in seven patients and M. canis in two. A test for recall antigen(Multitest CMI) showed suppression of cellular immunity in 3 cases. Treatment with griseofulvin or ketoconazole for 2-10 weeks was effective except one case. (Kor J Dermatd 1992;30(6):794-801)

[자료제공 : 네이버학술정보]
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