We herein report a case of palmar fibromatosis, who was 78-year-old male and had had multiple variable-sized subcutaneous hard nodules on the left palm for 2 months. Histopathologic findings of the lesion revealed that the nodules were highly cellular, containing numerous spindle shaped cells. Ultrastructurally, intracytoplasmic micrcfilaments were present, and the nuclei were extremely indented by one or more transverse folds. These findings suggested the cells were myofibroblasts. (Kor J Dermatol 28(5): 637-641, 1990)